Rosaceans

Oracea [Doxycycline]

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Oracea is a special prescription drug owned by Galderma that is the 'only oral prescription approved by the FDA for rosacea' and is doxycycline with an enteric-coated tablet that releases timed release beads of 10 Mg of doxycycline and 30 mg of immediate doxycycline. The claim is made that this low dose submicrobal is not antibiotic treatment but instead is anti-inflammatory. Nevertheless, you should read the product insert which comes with every prescription for Oracea which has the same warnings for doxycycline for risks and side effects. The safety limit tested for Oracea was nine months.

For anecdotal reports click here.

Oracea [Doxycycline] is a tetracycline used to treat inflammatory lesions caused by rosacea. Tetracyclines are often used to treat infections; however, this medicine will not treat infection. It works by reducing skin inflammation caused by rosacea. Doxycycline (INN) (pronounced /ˌdɒksɪˈsaɪkliːn/) [Other brand names include Monodox, Microdox, Periostat, Vibra-Tabs, Oracea, Doryx, Vibrox, Adoxa, Doxyhexal, Doxylin, and Atridox (topical doxycycline hyclate for periodontitis)] is a member of the tetracycline antibiotics group and is commonly used to treat a variety of infections. Doxycycline is a semi-synthetic tetracycline invented and clinically developed in the early 1960s by Pfizer Inc. and marketed under the brand name Vibramycin. Vibramycin received FDA approval in 1967, becoming Pfizer's first once-a-day broad-spectrum antibiotic. Other brand names include Monodox, Periostat, Vibra-Tabs, Doryx, Vibrox, Adoxa, Doxyhexal and Atridox (topical doxycycline hyclate for Periodontitis).
As well as the general indications for all members of the tetracycline antibiotics group, Doxycycline is frequently used to treat chronic prostatitis, sinusitis, syphilis, chlamydia, pelvic inflammatory disease, acne and rosacea. In addition it is used in the treatment and prophylaxis of Bacillus anthracis (anthrax) and in prophylaxis against malaria. It should not be used alone for initial treatment of malaria, even when the parasite is doxycyline-sensitive, because the antimalarial effect of doxycyline is delayed. This delay is related to its mechanism of action. Its mechanism of action against malaria is to specifically impair in the progeny the apicoplast genes resulting in their abnormal cell division.

Cautions and side effects
Cautions and side effects are similar to other members of the tetracycline antibiotic group. However the 10% risk of photosensitivity skin reactions is of particular importance for those intending long-term use for rosacea prophylaxis. Reports of GERD have been cited with the use of Doxycycline.
Unlike some other members of the tetracycline group, it may be used in those with renal impairment.
Previously, it was believed that Doxycycline impairs the effectiveness of many types of hormonal contraception due to CYP450 induction. Recent research has shown no significant loss of effectiveness in oral contraceptives while using most tetracycline antibiotic (including Doxycycline), although many physicians still recommend the use of barrier contraception for people taking the drug to prevent unwanted pregnancy. It should be taken with a full glass of water and patients should be upright for at least 30 minutes after administration to prevent irritation of the esophagus and stomach. Also, there is a slim risk of liver damage during prolonged use of the drug.
Doxycycline is not approved for use in children under the age of 8 years. It can cause permanent yellowing or graying of the teeth and can affect a child's growth. Specific exceptions are made for potentially fatal illnesses where the benefits outweigh the risks and there are few or no other alternatives, such as with Rocky Mountain spotted fever and anthrax. It should also not be used in pregnant and nursing women, as the drug can cause damage to a fetus and nursing child.

A report indicates that antibiotic "resistance to doxycycline can occur in a few days, with resistant bacteria in abundance after just seven days of treatment with 100 mg doxycyline daily according to a presentation at the Skin Disease Education Foundation Hawaii Dermatology Seminar. For more information on antibiotic resistance click here.

Source Wikipedia

An interesting video on Oracea which has some great animation can be found by clicking here.

You may want to read the negative comments about Oracea since it doesn't work for everyone.

Finally you may want to know about FREE ORACEA and SAVINGS CARDS and REBATES.

For more information, please visit this items webpage.

This item was added to our catalog on Monday 23 June, 2008.