The present invention results from my discovery of a causal link between the activation of the bradykinin pathway and rosacea. Accordingly, the invention features a method of treating or preventing rosacea by administering a compound that inhibits a component or components of the bradykinin activation pathway.

By "a nonsteroidal anti-inflammatory drug (NSAID)" is meant a compound that prevents or reduces inflammation. Preferred NSAIDs include, but are not limited to, naproxen, nabumetone, diclofenac, sulindac, oxaprosin, diflunisal, bromfenac, aspirin, piroxicam, indomethacin, etodolac, ibuprofen, fenoprofen, flurbiprofen, ketorolac, nimesulide, NS-398, ketoprofen, trisalicylates, acetominophen, oxaprosin, salsalate, rofecoxib, and celecoxib.

The present invention has the advantage of providing novel targets to regulate in the treatment of rosacea and to provide treatment alternatives to antibiotics. The antibiotics may have limited efficacy and cause adverse effects such as gastrointestinal intolerance, photosensitivity, the development of antibiotic-resistant infections, and yeast infections.

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